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BIOETHICS DICTIONARY - "R"s
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RABIES:
A bullet-shaped, single-stranded RNA virus of the order Mononegavirales
, family Rhabdoviridae , genus Lyssavirus , that
causes an acute, fatal brain disease in mammals. Transmission by
bite. The natural reservoir of rabies infection is in wild mammals,
but it can infect domestic animals and, incidentally, humans. (RW)
RAC: Recombinant DNA advisory
Committee of US NIH.
RACE: Level in the classification
of organisms. A species is divided into two or more races if there
are consistent observed differences between the races. So, for example,
the herring gull (a bird) is divided into several races. The Western
European race has a pale silver grey back and pink legs, while the
Eastern Scandinavian race has a dark slate grey back and yellow
legs. Both races belong to the same species and produce viable offspring
when interbred.
Until the 1960s most biologists were happy to
classify humans into a number of distinct races. Since then, though,
the term has increasingly fallen into disfavour. This is partly
because of the realisation that the genetic diversity within each
so-called human race is considerably greater than the genetic distance
between them, and partly because of the abuse of the term for political
ends, as, for example, in apartheid. (MR)
RACISM: the anti-social and erroneous belief that discriminatory treatment
of a particular group of human beings is (a) acceptable and (b)
that such discrimination can be justified on biological grounds.
Modern DNA sequencing data has established that within the human
gene pool there can be more variability within one population than
between different populations or "races", demonstrating significantly
that the human species belongs to one biological race divided into
many adaptively evolved local forms or varieties. (see MISOXENIA;
CHRONOCENTRISM) (IP+AG)
RADIATION: (Latin:
radiare "emit rays") 1. Physics: Particles such as alpha,
beta or gamma rays emitted from radioactive nuclear decay, or any
transmission of radiant energy such as solar power or electromagnetic
waves. (See RADIATION SICKNESS)
2. Biology: The divergence of an evolutionary lineage of organisms
into different niches by ecological radiation, or into different
phenotypes by adaptive radiation. (See ADAPTATION, NATURAL SELECTION)
(MP)
RADIATION SICKNESS: (See
RADIATION, RADIOACTIVITY)
RADIOLOGY: The branch of medicine
concerned with the use of x-rays, radioactive substances, and other
types of ionizing radiation in the diagnosis and treatment of disease.
(DM)
RADAR:
(Abbreviation for ‘RAdio Detection And Ranging’) Radar is the
utilization of echo-location using atmospheric radio waves, such
as airplane detection and car speed radars. (See SONAR) (MP)
RADIOACTIVITY: The chemical property of emission of radiation, and its measurement.
Radiation such as alpha rays (helium nucleus), beta rays (electrons)
and gamma rays (a form of electromagnetic radiation) are emitted
by unstable radioactive isotopes (radioisotopes) of uranium, thorium,
radium and most of the higher elements of the periodic table such
as the actinides. Radioactivity was discovered and developed by
scientists such as Roentgen, Rutherford, Becquerel and the Curies,
and is measured by a Geiger counter. (See RADIATION, ELECTROMAGNETIC
RADIATION, CURIE) (MP)
RADIOCARBON
DATING: the determination of the age of carbon samples embedded
in objects of plant or animal origin by means of their content of
radioactive C14 carbon (see optical and thermoluminescence
dating). (IP)
RAINBOW SERPENT: the
giant snake is one of the more common forms utilized by the Australian
Aboriginal Dreamtime Spirit Ancestors (see Dreamtime and Dreaming).
In the North and Center of Australia, it was at the time of creation
that the serpent began to move through the landscape marking its
unique features; for example, the black rock snake called Kurrichalpongo
from the Roper River country in the Northern Territory first carved
out the rivers, rock formations, mountains and bush, then ascended
into the sky turning into the rainbow serpent to guide down thunder
and lightning to flood the land. The Rainbow Serpent’s jo
creator called "Biamee." (see SACRED SITES) (IP)
RAINBOWS: are
produced by refraction and reflection of the sun’s rays by
millions of falling raindrops. Rainbows arRONAS AND GREEN FLASH).
(IP) There is an international group called the Rainbows, who believe
in peace, equality, nudism (q.v) and free love. They hold
gatherings regularly in different countries, perhaps as often as
once a month.(FL)
RAINFORESTS: See
RAINFOREST DESTRUCTION, TROPICAL RAINFOREST AND TEMPERATE RAINFOREST.
RAINFOREST DESTRUCTION: See
TROPICAL RAINFOREST.
RANDOM:
Random means an uncertain or equally probable choice or outcome,
without pattern and dictated by chaos or chance. Randomization is
experimental selection or sampling using chance. Random factor implies
an independent variable with random treatment level. Random error
is noise. (See RANDOM SAMPLING) (MP)
RANDOM SAMPLING: The
use of samples with equal probability of selection from the statistical
population. This is the most common method for approximating a representative
sample to allow accurate inferences. (See REPRESENTATIVE SAMPLE,
STATISTIC) (MP)
RANDOM
SELECTION: The use of chance in allocating research subjects
to treatment groups. (DM)
RANDOMNESS: See
CHAOS THEORY, RANDOM SAMPLING.
RANGE:
1. Ecology: Species distribution, often excluding vagrant individuals
and some proportion of territory within the outer range. 2. Statistics:
The range of a data set is the difference between the highest and
the lowest values in the set. It depends on the extremity of the
end values. The interquartile range is anther measure of dispersion;
the difference between the third and first quartiles. (See POPULATION
DISTRIBUTION, OUTLIER, PERCENTILE, MEASURES OF DISPERSION) (JA &
MP)
RAPE:
Forcing another person to have sex. While legal and other methods
should be used to protect women from rap e, it is worth trying to
see whether the incidence of rape can be reduced if more women were
to learn martial arts on a serious level. (FL)
RATE-LIMITING
FACTOR: See LIMITING FACTOR.
RATING
SCALE: See LIKERT SCALE.
RAW DATA: Measurement
values taken directly from the measuring instrument. (See DATA,
MEASUREMENT) (MP)
REAFFORESTATION:
Establishment of forest on deforested land. Chiefly British
and Australian word; the American form is Reforestation. (See TREE
PLANTING, RESTORATION ECOLOGY). (RW)
READING:
There is more to reading than meets the eye, just as there is
more information than can absorbed in one lifetime. The essential
concept in ‘speed reading’ is not to ‘read aloud’ words in your
mind, a natural limit to your reading rate. Instead take in chunks
of text at once – a concept at a time – absorbing the information
without ‘hearing’ it in words. Useful related attributes are ‘scanning’
(reading ‘past’ the text to identify certain keywords), ‘skimming’
(quickly reading headlines and first paragraphs to ‘get the gist’),
and ‘referencing’ (using thehe imagination, allowing pause for reflection,
developing thought and emotion, and of course providing pleasure.
(See TELEVISION, INTERNET) (MP)
REC:
Research Ethics Committee, United Kingdom, which includes both
the Local and Multi-centre Research Ethics Committees. (JA)
RECALL: Remembrance by a patient
or research subject of information given orally or in writing. (DM)
RECESSIVE: A trait or condition
which is only expressed in individuals who have two identical versions
of a particular gene, one inherited from their mother, and one from
their father. (Contrast to DOMINANT) (DM)
RECIPROCITY:
A reciprocal, or mutually beneficial two-way relationship between
individuals or nations. Reciprocity is close to a universal ethical
principle, with versions of the ‘Golden Rule’ common to most religions.
The golden rule takes reciprocity a step further, treating others
well irrespective of any past relationship. (See GOLDEN RULE) (MP)
RECLAIM THE STREETS: A large self-organizing
community campaign which promotes road access for pedestrians, night-time
safety and reduced automobile dependence. ‘Reclaim the Streets’
is a large rally and social gathering in which pedestrians simply
block off roads at their allocated time and take over the streets
of a certain area. (See CRITICAL MASS, CIVIL DISOBEDIENCE, ACTIVISM)
(MP)
RECOMBINANT
DNA: Hybrid DNA sequences assembled in vitro from different
sources; or hybrid DNA sequences from the same source assembled
in vitro in a novel configuration. Research using biologically
active DNA which has been formed in the laboratory by the joining
of segments of DNA from different sources. (DM)
RECOMBINANT DNA ADVISORY COMMITTEE (RDAC):
A
Competent authority/committee of the Department of Biotechnology
to review developments in biotechnology at national and international
levels and to recommend suitable and appropriate safety regulations
for a country (India) in recombinant research, use and applications
from time to time. (JA)
RECOMBINANT DNA TECHNOLOGIES: Procedures
used to join together DNA segments in a cell-free system (an environment
outside of a cell or organism). A recombinant DNA molecule can enter
a cell and replicate there, either autonomously or after it has
become integrated into a cellular chromosome. (See DNA HYBRIDIZATION
TECHNOLOGY) (DM)
RECOMBINANT ORGANISM: See GMOs.
RECOMBINATION: The
formation of a new association of genetic material. It is usually
applied to the process of meiosis, during a stage of which the genetic
material packaged into gametes is mixed and reconstituted in any
of an enormous number of possible combinations. It is also applied
to genetic engineering. (DM)
RECONCILIATION: To re-establish friendship between differing parties; to resolve,
settle or bring to agreement 2. in Australia a community response
stemming from past practices of segregating and marginalizing its
Aboriginal and Torres Strait Islander communities by systematically
dispossessing them of their land, separating them from their children
and disconnecting them from their culture and language. In this
instance, reconciliation requires a sense of history with the most
common theme being for white Australia to learn and understand the
truth, and to apologize for the shameful legacy of Australia's history
prior to the abolition of Terra Nullius. (IP)
RECREATION OPPORTUNITY SPECTRUM (ROS): A
regional classification tool which compares recreational opportunity
at different sites according to environmental modification, human
induced controls, human usage and motorization. The objectives of
the ROS are to associate activity preferences and user profiles
to appropriate recreational settings. Classes used range from primitive/remote,
semi-primitive, roaded-natural, rural, through to urban/developed.
(See TOURISM, SUSTAINABLE TOURISM) (MP)
RECREATIONAL DRUGS: See DRUG DEPENDENCY.
RECYCLING: Remanufacturing of waste by-products to once again produce useful
materials. It is now possible for industry to close the loop of
waste by recycling resources numerous times. Efficient recycling
practices minimise the destructive removal of new raw materials
from the environment and reduce the need to dispose of contaminated
wastes. (See REDUCE, RE-USE) (MP)
REDEMPTIVE INTERVENTION: reverses
an immediate consequence of unwise human action.
REDUCE: The
first and perhaps most important term in the mantra "Reduce, Re-Use,
Recycle", referring to the necessity of lowering the levels and
rates of human consumption. Valuable resources are wasted by unnecessary
products and packaging, conspicuous consumption, and desires artificially
induced by advertising. Such things must be reduced at both the
personal and production levels. (See
RE-USE, RECYCLING, CONSPICUOUS CONSUMPTION, DEMATERIALIZATION)(MP)
REDUCTIO
AD ABSURDUM: Latin for “reduction to absurdity”, reductio
ad absurdum, related to quasi-reductio, refers to refutation
of an argument by reducing it to simpler elements thus exposing
hidden absurdity. (See FALLACIES, PROOF) (MP)
REDUCTIONIST:
based on the assumption that the whole can be explained in
terms of its parts; for example, science is reductionist.
REFERENDUM:
A people’s vote which determines an issue of policy directly,
as distinct from an election of political representatives to make
the decision. The ‘Citizen’s Initiated Referendum’ is a form of
direct doliticians almost entirely. (See DIRECT DEMOCRACY) (MP)
REFORESTATION:
See REAFFORESTATION.
REFUGEES: See POLITICAL REFUGEES.
REFUSAL TO TREAT: Refusal by a health professional or a health facility to treat
a patient because of bias or fear of infection (differentiate from
SELECTION FOR TREATMENT, in which questions of resource allocation
or of the efficacy of treatment are involved, and from TREATMENT
REFUSAL, which originates with the patient rather than with the
health professional). (DM)
REGIONAL ETHICS COMMITTEES:
Committees established to protect the welfare of patients or research
subjects at two or more facilities in the same geographic area.
(DM)
REGIONAL
MANAGEMENT: Policy direction, integrated management and monitoring
of indicators at the appropriate macro-scales of bioregions (bioregionalism),
habitats (conservation), ecosystems (ecology) or catchments (total
catchment management), across terrestrial and marine environments
(coastal zone management), and across large political boundaries
(regional security). (See BIOREGION, BIOREGIONALISM, INTEGRATED
MANAGEMENT, TOTAL CATCHMENT MANAGEMENT, MACRO-) (MP)
REGRESSION ANALYSIS: Regression analysis determines the relationship between two variables
(the regression equation), and uses the least-squares method to
find the line of best fit. Linear regression determines the straight
line of best fit, and curvilinear regression determines the curve
of best fit. Analysis of covariance combines analysis of variance
with regression analysis. (See STATISTICS, CORRELATION, FREQUENCY
DISTRIBUTION, CHI-SQUARE TEST, ANALYSIS OF VARIANCE) (MP)
REHABILITATION:
Restoration of function, to the maximum degree possible, of
persons suffering from disease or injury. (DM)
REINCARNATION:
According to the Doctrine of Reincarnation, or Transmigration of
Souls, the soul lived in another body before birth, and will be
reborn in yet another one after death. According to surprisingly
similar theories in Israeli Kabala (Jewish Mysticism) and in Hinduism,
souls are reborn any number of times in order to learn lessons or
to undergo repair ( tikkun , in Hebrew). This process will
continue until the soul reaches perfection. One might be reborn
as another human being, or as an animal, plant, rock or whatever.
According to some versions, the people with whom one is in contact
today are people with whom we were in contact in previous lives
and places. We have met again in order to work out various tasks,
lessons or repairs. Believers in reincarnation sometimes say that
when we meet a stranger, and immediately find ourselves understanding
one another and discussing deeply, we are not starting a new conversation
but continuing one from a previous life.
In clinical ethics, a believer in reincarnation
might hesitate to stop life saving treatment of, for example, a
neonate with extremely severe anomalies: for perhaps living in such
a way for even a short period of time will provide exactly the lesson
which that soul needs. And if it doesn't do it in this lifetime,
it will have to do so in another. So nothing will have been gained
by stopping treatment.
Reincarnation is a doctrine, which can neither
be proved nor disproved. We must wait to see what happens after
death. And perhaps we won't see anything at all. Or perhaps we shall
be surprised in amazing way. About that which we cannot know, a
scientific attitude demands that we admit our ignorance, and approach
life's decisions with the humble awareness that possibilities of
which we can know nothing might be true.
Although belief in reincarnation is widespread
among religious Jews, not all accept it. One distinguished opponent
was Rabbi Saadia Gaon. (FL)
REINFORCING
FEEDBACK: See FEEDBACK.
RELATIVITY THEORY: See EINSTEIN, ALBERT.
RELIGION:
Religion is about human meaning - an attempt to explain the
peculiarity of our existence on this intermediate plane between
gods and animals, between the infinite and oblivion. Religion is
based on belief not scientific fact. (See RELIGIONS, LIVING RELIGION,
RELIGIOUS EDUCATIONS, SCIENCE AND RELIGION) (IP)
RELIGIONS: The
world contains a diversity of religions and belief systems which
can be classified in a number of ways. Early religious belief systems
included various forms of shamanism, animism, Gnosticism, paganism
and polytheism. Of the major monotheistic religions, Judaism gave
rise to Christianity based on the teachings of Jesus Christ, and
Islam based on those of Muhammad. Muslims may be Sunni or Shiah
(Shiite), Christians may be Catholic, Protestant or Orthodox. Asian
religions include Hinduism, Buddhism, Confucianism, Taoism and Shinto.
Followers of the philosophy of Buddha may be Mahayana, Hinayana
(Therevada) or Zen Buddhists. More recently there has been a resurgence
of monism ("all is one" philosophy), pantheism (the universe is
a manifestation of God), indigenous beliefs (respect for the Earth)
and New Age spirituality (self-styled belief systems). Other religions
include Zoroastrianism, Kabbala (mystical Judaism), Sufism (mystical
Islam), Brahmanism, Jains, Sikhs, Hare Krishna, Baha'i, Mormon,
Anglican, Jehova's Witness, Rastafarians, Scientology, Falun Gong
and various 'cult' followings. Also, atheism is non-belief in God,
and agnosticism is an open mind in recognition that such things
are beyond one's capacity to know. The religions of the world are
a diversity of philosophies with a common theme, and should not
be used as an excuse for prejudice or conflict. Movements such as
theology, comparative religion and international religious forums,
institutions and Unions of Churches are progressing global culture
towards a time of religious tolerance and respect where philosophical
ideas are shared rather than enforced or used to promote division.
(MP)
RELIGIOUS EDUCATION: In many parts of the world the topic of religious education remains
a most controversial issue. Historically the early education of
children was provided in India by the Brahmins (Hindu religious
leaders), in Buddhist countries by the monks, in Islamic countries
by the Mullahs and in Christian countries by the priests. However,
the rise of secularism has created controversy as to the control
of education. In countries such as the Netherlands and Australia
groups of parents wishing to set up denominational schools receive
by the government tax-funded running costs. Typically, as in the
UK and Australia, the only prescribed subject in the curriculum
of public (local education authority) schools is a general religious
instruction where an agreed syllabus is worked out in consultation
with various denominations. Parents, if they want, have the right
to withdraw their children from this religious education. In the
USA interpretations of the constitution have separated Church and
State and parochial schools receive no public funding. (See EDUCATION,
MEDICAL EDUCATION, QURAN, BIBLE) (IP)
REMOTE SENSING: The
collection of information about the Earth surface from a distance,
for example with aeroplane photos or satellite data. Spatially referenced
data is displayed and analysed by image processing software, interactive
mapping systems and Geographic Information Systems. Remote sensing
allows monitoring of military activities, land uses, vegetation
types, geology, habitat integrity, ecological impacts and other
changes related to environment and development. (See GEOGRAPHIC
INFORMATION SYSTEMS) (MP)
REMUNERATION: Payment
for a service or for a commodity such as a body part. (DM)
RENEWABLE ENERGY: Energy supplies derived from natural sources able to regenerate
themselves, thereby enabling sustainable long-term consumption of
energy by humans. (See SOLAR, WIND, GEOTHERMAL & BIOMASS ENERGY,
HYDROELECTRIC POWER, RENEWABLE ENERGY TECHNOLOGIES) (MP)
RENEWABLE ENERGY TECHNOLOGIES: New
technologies which generate power from sustainably managed renewable
sources. The development of renewable energy technologies should
be encouraged and subsidised. Long-term supply of private and industrial
energy will require the replacement of old, polluting technologies
such as coal-fired power stations, with new renewable energy technologies
such as solar panels, wind turbines, alternatively-powered vehicles
and energy generated from the sea. (See RENEWABLE ENERGY) (MP)
RENEWABLE RESOURCES: Natural resources which
are able to replenish or regenerate themselves within a similar
time frame to their utilization by humans, thereby enabling sustainable
long-term consumption. Examples include sustainably managed fisheries
and the cultivation of plantation timbers. (See RESOURCE, RENEWABLE
ENERGY, NON-RENEWABLE RESOURCES) (MP)
REPETITIVE
STRAIN INJURY: RSI is long-lasting injury to the muscles, joints,
tendons or bone structure caused by extended or excessive repeated
motions, for example in those who operate machines or computer keyboards.
Ergonomic furniture, stretching, task rotation and frequent breaks
help prevent RSI. The responsible worker and ethical workplace will
ensure that working environment and schedules will not cause RSI
in subsequent life. (See ERGONOMICS) (MP)
REPLICATING ASSEMBLER: See
ASSEMBLER.
REPLICATION: 1.
In statistics and experimental design, replication is the use of
a significantly large number of experimental subjects, repeats of
the treatments or observations, and duplication of the research
methods. (See REPRESENTATIVE SAMPLE, EXPERIMENTAL GROUPS, CONTROL
GROUPS) 2. One of the defining qualities of life, replication is
the ability to make copies of oneself. (See REPLICATOR, LIFE) 3.
The synthesis of new DNA strands from existing DNA. In human beings
and other eucaryotes, replication occurs in the nucleus of a cell.
(See DNA) (DM & MP)
REPLICATOR:
A complex structure able to copy and reproduce itself using
materials from its surrounding environment. This often implies identical
replication, although many replicators copy with variation. Examples
of replicators include some chemicals (e.g. crystal structures),
genetic code (e.g. RNA, DNA), organisms (e.g. plants, humans), information
(e.g. memes, ideas) and software programming (e.g. computer viruses,
artificial life). Replication is one of the essential definitional
components of life. (See REPLICATION, ORIGIN OF LIFE) (MP)
REPRESENTATIVE SAMPLE: A
sample from a statistical population must be characteristic of that
population for accurate inferences to be made. For the sample to
be representative it must include sufficient instances of all the
different categories or classes typical of the population as a whole.
This is usually achieved through random sampling, and may either
be improved or biased by stratifying the random sampling across
specified groups, areas or times which have been deemed representative.
(See SAMPLE, STATISTIC) (MP)
REPRODUCTION: See PROCREATION.
REPRODUCTIVE CLONING: Use
of CLONING (q.v.) technology to produce one or more individuals
genetically identical (apart from the genes in MITOCHONDRIA (q.v.)
and CHLOROPLASTS (q.v.)) to another individual. In the late 1990s
reproductive cloning was used to produce clones of the adults of
a number of mammalian species, including sheep, mice and pigs. The
most famous of these was DOLLY (q.v.). Many countries rushed to
outlaw the possibility of reproductive cloning in humans. Most bioethicists
supported such bans though a minority were more ambivalent. (MR)
REPRODUCTIVE FREEDOM: All
couples and individuals have the basic right to decide freely and
responsibly the number and spacing of their children and to have
the information, education, and means to do so. As stated in the
1984 UN recommendation on basic human rights. (DM)
REPTILIA: The class of vertebrates breathing air with lungs, and having external
scales or horny plates. Extant taxa include the turtles, crocodiles,
lizards, and snakes, though reptilian phylogeny is a matter of some
controversy. (RW)
REQUIRED REQUEST: An
organ procurement policy based on the requirement that health personnel
routinely make inquiry of family members about the possibility of
removing organs from a patient who has been declared legally dead.
(DM)
RES NULLIUS: in
Latin "belonging to no one" (see AUSTRALIAN ABORIGINAL & NATIVE
TITLE LEGISLATION - AUSTRALIA). (IP)
RESEARCH
AND DEVELOPMENT: Research and Development (often abbreviated
to R&D) is the exploratory process of research and scientific
discovery. Allocations of research funding (or more correctly, the
lack thereof) are one of the most popular subjects for jokes and
complaints in the scientific and academic communities. The ‘Frascati
Manuals’ are periodic OEethical consider PRINCIPLE, TECHNOLOGY)
(MP)
RESEARCH
ETHICS COMMITTEES: Institutional committees established to protect
the welfare of research subjects. (See ETHICS COMMITTEE) (DM)
RESIDENTIAL FACILITIES: Facilities
that provide supervision and assistance in activities of daily living.
(DM)
RESILIENCE: ecology - The tendency of an ecosystem to maintain a stable
state despite disturbance. (RW)
RESISTANCE TO CHANGE: See
TECHNOLOGY.
RESOLUTION: Degree of molecular detail
on a physical map of DNA, ranking from low to high. (DM)
RESOURCE: A
source of supply for some human necessity, deficiency or desire.
Resources may be stocks or reserves, information, aid or support,
material, energy or features of the natural environment. Excessive
demands on natural resources are currently placing global ecosystems
under threat, particularly as a result of habitat destruction and
degradation with its associated loss of biodiversity. Resource consumption
can only endure over the long term if current non-renewable resources
are able to be replaced with the sustainable management of alternative
renewable resources. (See NATURAL CAPITAL, RENEWABLE RESOURCES.)
(MP)
RESOURCE
ALLOCATION: Societal or institutional decisions about the distribution
of available resources, for example water allocation between the
needs of irrigation farmers and riverine ecosystems, or resource
allocation to and within government policies, research programs,
education institutions, health care and medical resources. (See
RESOURCE) (DM & MP)
RESOURCE-BASED PRICING: Pricing
of goods and services which reflects the environmental and social
costs of the associated extraction of natural resources and production
of the product. This provides a monetary disincentive to production
processes which are environmentally damaging. (See RESOURCE) (MP)
RESOURCE PARTITIONING: See
HABITAT PARTITIONING.
RESPECT:
Show regard, consideration or esteem for; that is, refrain from
interfering with. (see RESPECT FOR LIFE) (IP)
RESPIRATION: (Latin
respirare 'to breathe'). The term can be applied to the events
which occur at the level of the whole organism (i) or its constituent
cells (ii). (i) The breathing pattern or rhythmic inflation and
deflation of the lungs which maintains a steady concentration of
oxygen and carbon dioxide for cellular metabolism. The control of
respiration is partly chemical and partly nervous. (ii) Cellular
respiration - the oxidation of the end products of glycolysis (the
enzymic breakdown of glucose to pyruvic acid) to carbon dioxide
and water (the tricarboxylic acid cycle) with the generation of
36 molecules of ATP per glucose molecule. Aerobic respiration involves
the molecular exchange of oxygen and carbon dioxide within the body's
tissues. (See PHOTOSYNTHESIS) (IP)
RESPONSIBLE: 1.
legally or ethically accountable for the care or welfare of another
2. involving personal accountability or ability to act without guidance
or superior authority; that is, answerable for one’s own behavior
by being capable of making rational or ethical decisions 3. being
the source or cause of something 4. able to be trusted or depended
upon, being reliable 5. based upon good judg sound thinking. (IP)
RESPONSIBILITY:
The act of being responsible (e.g. reliable); accountability
(e.g. in law); ownership of the success or otherwise of an undertaking
(e.g. business practices); responsibilities are the equal partner
of rights - those with human rights are the ones who have the power
and therefore the responsibility for those without rights. (See
RESPONSIBLE) (MP)
RESTORATION
ECOLOGY: Rehabilitation of ecological components of land previously
degraded by humans. Reconstruction of a damaged site involves environmental
reclamation including the removal of infrastructure, clearing of
potential pollutants, and contouring of the land surface and topsoil.
Ecological rehabilitation then includes local ecosystem research,
bioremediation, nursery, planting and maintenance of appropriate
trees, reforestation, habitat restoration, fauna management and
ecosystem monitoring. Restoration ecology is an important final
component of any extractive development process such as mining or
forestry. Restored ecological systems are usually less natural and
diverse than originals, and should be considered an adjunct to habitat
preservation. Many ecologists are philosophically predisposed to
conservation rather than restoration. (See BIOREMEDIATION, TREE-PLANTING)
(MP)
RESTRICTION ENZYME, ENDONUCLEASE: A
protein that recognizes specific, short nucleotide sequences and
cuts DNA at those sites. There are over 400 such enzymes in bacteria
that recognize over 100 different DNA sequences. See restriction
enzyme cutting site. (DM)
RESTRICTION ENZYME CUTTING SITE: A
specific nucleotide sequence of DNA at which a restriction enzyme
cuts the DNA. Some sites occur frequently in DNA, every several
hundred base pairs, but others occur much less frequently, may be
every 10,000 base pairs. (DM)
RESUSCITATION: The
reviving of patients from unconsciousness or apparent death, e.g.,
by restoration of breathing after respiratory arrest or of heartbeat
after cardiac arrest. (See DNR, EMERGENCY CARE, RESUSCITATION ORDERS)
(DM)
RESUSCITATION ORDERS: Instructions, policies,
and decision making regarding the reviving of patients whose respiration
and/or heartbeat have stopped. (See DNR ORDERS) (DM)
RETROVIRUS: A
family of Viruses whose genetic material is RNA and is further characterized
by the presence of reverse transcriptase in the virion. They can
convert RNA to DNA and back to RNA. HIV is a retrovirus. (DM)
RE-USE: This
term in the phrase "Reduce, Re-Use, Recycle" refers to using goods
and materials again rather than discarding or replacing them. Appreciate
items for their usefulness and function rather than their newness
and fashion. This form of direct recycling requires no expenditure
of energy in the processes of remanufacture. (See REDUCE, RECYCLING)
(MP)
REVIEW COMMITTEES: See
ETHICS COMMITTEES.
REVIEW COMMITTTE ON GENETIC MANIPULATION
(RCGM): A
Competent authority/committee of the Department of Biotechnology
to monitor the safety related aspects in respect or on-going research
projects and activities involving genetically engineered organism/hazardous
microorganism. It is members may be drawn from other Government
departments such as Indian Council of Medical Research. The function
of review committee may include prescribing the procedures, restricting
or prohibiting production, sale importation and use of such genetically
engineered organisms and their cellular components. (JA)
REVERSE GENETICS: Process
that involves production of DNA from RNA in the reverse direction
to the central dogma of molecular biology. Applied to consider the
genetic technology of producing living organisms from dead (frozen
/preserved in alcohol) organism's DNA materials, e.g. Frozen mammoth.
(DM, JA)
REVERSE TRANSCRIPTASE: An enzyme capable of directing the production of a single-strand
DNA copy form an RNA template. (DM)
REVOLUTIONARY:
An adjective describing revolution, or a noun describing an
individual involved in ideological activism and revolution. From
the authoritarian communalistic perspective, the revolutionary is
a violent or reactionary menace. For the individualist however,
the word often puts a positive connotation on the act of civil disobedience
or resistance against oppression. (See FREEDOM FIGHTER, ACTIVISM,
TERRORISM) (MP)
RFLP,
RESTRICTION FRAGMENT LENGTH POLYMORPHISM: Variation in DNA fragment
sizes cut by restriction enzymes; polymorphic sequences that are
responsible for RFLPs are used as markers on genetic linkage maps.
(DM)
RHYTHM METHOD OF CONTRACEPTION: The
avoidance of sexual intercourse near the middle of a 28-day cycle
when an egg is most likely to be present in the oviduct but this
method is not safe and is best combined with some other method of
contraception. (See NATURAL FAMILY PLANNING METHODS) (IP)
RIBONUCLEIC ACID: See
RNA.
RIBOSOMAL RNA, rRNA: A class of RNA found
in the ribosomes of cells, and is a ribasomes primary constituent.
Ribosomes are the protein-manufacturing organelles of cells. They
exist in the cytoplasm and are attached to the membrane of the endoplasmic
reticulum. rRNA is transcribed from DNA, like all RNA, and it is
processed in the nucleolus before being transported through the
nuclear membrane in eukaryotes. This type of RNA constitutes the
vast majority of RNA found in a typical cell (upwards of 95%). While
proteins are also present in ribosomes, 23s rRNA forms the active
site for peptide bond formation, making that molecule a ribozyme.
(RD)
RIBOSOME: The
small cellular organelle where polypeptides are assembled from amino
acids based on messenger RNA templates. (RW)
RICIN: A
deadly toxin obtained from castor bean Ricinus communis that
produces agglutination of red blood cells and hemorrhage of the
respiratory and gastrointestinal mucosa. The toxin has been used
as a biological weapon in the hands of terrorists. (see BIOLOGICAL
WARFARE) (IP)
RIGHTS: A
right might be defined as the freedom to do what one has a duty
to do. This might be the freedom which one actually has, or the
freedom, which one ethically ought to have. The former may be called
positive rights , and the latter ethical rights .
If one believes in the Bible, or a similar doctrine according to
which God commanded things to exist, and commanded plants, animals
and humans also to be fruitful and multiply, then everything --
including rocks, water and fire -- will have a right to exist, and
plants, animals and humans will also have a right to be fruitful
and multiply. Sometimes duties, and therefore also rights, come
into conflict. I cannot exist unless I eat other creatures and deprive
them of their duties and rights to exist. I have, however, no more
rights than my duties require. So I have no right to eat more than
what I must eat in order to be healthy and survive. Certainly if
we have a right at all to kill animals for meat, we have no right
to a milligram more meat than we need for health. If some people
need less meat than others, they have less of a right to it.
If we do not believe in the Bible or any other metaphysical source
of duties, it is much harder to prove the existence of ethical rights.
Indeed the great theorists of natural and inalienable rights, like
John Locke and the framers of the United States Declaration of Independence,
believed in God. Without such belief, someone else may contradict
anyone's claim to a right or a duty, with no clear method to decide
the argument other than by a contest of power. In such a case, only
positive rights will exist. And only those who manage to fight for
rights and win will have them. (FL)
RIGHT TO DIE: A right claimed by patients or their representatives to make decisions
with regard to the patient's dying, such as by refusing life-sustaining
medical care or by requesting assistance in dying. (See ADVANCE
DIRECTIVES). (DM)
RISK:
The probability of adverse effects, their nature, and their
severity over a range of exposures. For example, a function of the
probability of an adverse health effect and the severity of that
effect, consequential to a hazard(s) in food. A risk is an expected
danger or a problem situation around the corner, due to the introduction
of a new technological situation, e.g. introduction of GM crops/antibiotic
resistance due to the proliferation of drugs, interspecies transfer
of genes, creation of new bioweapons -pathogenic organisms, crop
failure, reduction in biodiversity, privatization of natural resources
and patenting. (DM, JA)
RISK
ANALYSES: See RISK ASSESSMENT, RISK MANAGEMENT AND RISK COMMUNICATION.
RISK ASSESMENT: Science
of understanding hazards - identification, possibility of their
occurrence ad the consequence of such occurrence. i.e. characterizing
the risk. (JA)
RISK COMMUNICATION: The
interactive exchange of information and opinions concerning risk
among risk assessors, risk managers, consumers and other interested
parties. (JA)
RISK MANAGEMENT: If the assessed risk is dangerous then it includes weighing policy,
selecting, implementing control options, regulatory measures. (JA)
RISK/BENEFIT: A
decision-assisting process that attempts to identify, estimate and
weigh all the risks and benefits associated with a particular action
and to determine whether overall the benefit would be worth the
associated risk. (DM)
RITALIN: See
RITALIN HYDROCHLORIDE.
RITALIN HYDROCHLORIDE: Trademark
for methylphenidate hydrochloride, a central nervous system stimulant
that has been used successfully in the treatment of children suffering
from attention-deficit hyperactivity disorder. The drug acts by
stimulating the brain to increase the amount of dopamine available
to it, however, there are side effects associated with this treatment
including growth retardation, insomnia, decreased appetite and nervous
tics. Therefore, medicating young people is controversial; especially
in the absence of more severe mood disorders it should not be forgotten
that high levels of activity, precociousness and curiosity are often
simply normal childhood characteristics. (See ATTENTION-DEFICIT
HYPERACTIVITY DISORDER). (IP)
RNA, RIBONUCLEIC ACID: A chemical found in the nucleus and cytoplasm of cells; it plays
an important role in protein synthesis and other chemical activities
of the cell. There are several classes of RNA molecules, including
messenger RNA, transfer RNA, ribosomal RNA and other small RNAs,
each serving a different purpose. Contains uracil as a base pair.
Similar to DNA in structure and plays an intermediary role in converting
information from DNA to ribosomes where proteins are made. (DM,JA)
RNAi: Double
stranded interference RNA, can destroy messenger RNA sequence, can
slice any gene. (JA)
ROBOT: (Czech: robota "work"
or "servitude") An automated electromechanical device imitative
of human anatomy or actions, often with programming to perform certain
human-like functions such as perception and manipulation. The term
was coined by Karel Capek, robots defined in his 1920 play Rossum’s
Universal Robots as mass-produced mechanical humanoids
for cheap labor. Since then robots have become a staple of fiction,
popular culture, science, technology and work. About half of the
world’s operational robots are in Japan, with the world robot
population in 2000 roughly 1 million. Most of the robot workforce
are non-complex "dumb" robots engaged in repetitive taerform humans
in speed, strength, stamina and precision, and are used in the commercial
production of cars, electronics and chemicals. An "intelligent"
robot uses its sensory apspond and adapt as well as follow its programming.
Robots can work in hazardous, extreme or remote environments such
as the exploration of space (probes) and the deep sea (aquaby contributes
to prosthetics and bionics (cyborgs), and the design of robots often
imitates the human form (androids). Some parents have interactive
robot dogs as pets, and the is eagerly anticipated by others. Modern
snake-like robots used for earthquake rescue are comprised of numerous
interchangeable segmented units acting as a network. Robot spy-pssiles
are currently used in international conflict. In the future self-replicating
robots constructed from atoms and molecules (nanobots) may swarm
the battlefield or sweep theerol and other illnesses. (See ANDROID,
AQUABOT, CYBORG, NANOBOT, ROBOT BUSH, ROBOT ETHICS, ROBOTICS) (MP)
ROBOT BUSH: A
hypothetical thought experiment by Hans Moravec in Mind Children:
The Future of Robot and Human Intelligence, designed to illustrate
the outermost extremes of potential advancement in robot technology.
"A bush robot would be a marvel of surrealism to behold." It capitalizes
on the manipulative utility of limbs and fingers, being comprised
of numerous such extensions into smaller and thinner branches and
then cilia. These dexterous self-constructing mechanical joints
would be so numerous as to give the robot "organic" flexibility.
The adaptable leaf fingers are antennae able to radio-communicate
and sense forces, movement, electromagnetics and light among other
things. With artificial intelligence and coordinated neural networking,
they could divide into a swarm of smaller units which could burrow,
swim, fly like insects and collect environmental data relevant to
the parent robot’s knowledge and survival. Taken further,
the fingers could subdivide down to the realm of nanotechnology,
in which case the abilities of such a robot would truly appear like
magic. (See ROBOT, NANOTECHNOLOGY) (MP)
ROBOT
ETHICS: The flipsides to ethics in relation to robots and artificial
intelligence are: 1. How should we treat them, and 2. How will they
treat us? Robots and androids like ‘ R2D2 ’ and ‘Atom’ (Astroboy)
are already considered ‘part of the family’ by younger
media viewers in places like Japan and America. But where do we
draw the line with our machines and start treating them humanely
- when they can ask us not to turn them off? Will they consider
ethics in their own attempts at survival? Isaac Asimov proposed
his Three Laws of Robotics in 1942: “1) A robot may not injure a
human being, or, through inaction, allow a human being to come to
harm; 2) A robot must obey the orders given it by human beings except
where in conflict with the first law; 3) A robot must protect its
own existence except where in conflict with the first or second
law.” The fear is that learning machines may not be that easily
‘programmed’ (e.g. Terminator or ‘Hal’ in 2001 ).
The combination of human and machine (bionics, microchip implants,
creation of cyborgs) provides another dimension relevant to medical
bioethics. (See ROBOT, ROBOTICS, ARTIFICIAL INTELLIGENCE, BIONICS,
CYBORG, MICROCHIP IMPLANT) (MP)
ROBOTICS: The
science and technology of robot design, engineering and operation,
combining artificial intelligence with mechanical engineering. Each
requirement of a robot has technology to match, for example seeing
(video), hearing (audio), perception (radio-waves), understanding
(face/speech recognition), walking (locomotion), manipulation (cybernetic
networks), problem-solving (heuristics, expert systems), thinking
(artificial intelligence), action (robot body), interaction (learning
procedures) and self-evolution (artificial life). Robotics has the
job of integrating such functions, including both design/engineering
and programming for dealing with the environment. Experimental robotics
is conducted for example at NASA and MIT and by Japanese technology
companies, surveyed by the International Federation of Robotics.
The field of robotics is applied to business (e.g. consumer robots),
policy (e.g. expert systems), medicine (e.g. bionics, cyborgs),
engineering (e.g. cybernetics), industry (e.g. assembly-line), hazardous
work (e.g. radioactive materials, bomb disposal), military (e.g.
autonomous vehicles, missiles) and exploration (spacecraft, submersibles).
Robotics may provide economical exploration of the solar system
with larger numbers of smaller robotic space probes. Robotics presents
its greatest risk to humans when applied to artificial intelligence
(AI), providing computers with thinking and learning ability, senses
and a ‘body’ witf armed robotic vehicles or nanobots possible in
future combat. (See ROBOT, ARTIFICIAL LIFE, ARTIFICIAL INTELLIGENCE,
CYBERNETICS, BIONICS, NANOTECHNOLOGY) (MP)
ROBOTIC WARFARE: See
VIRTUAL WARFARE.
ROBUST: Able to withstand utilization;
for example robust machinery is tough and long-lasting, and a robust
model is able to stand up to model testing such as sensitivity analysis.
(See SENSITIVITY ANALYSIS) (MP)
ROLE
PLAYING: Is a method to discover the best approach for
a problem and is the most often used in business, industry and education.
In general it is not aimed at discovering the deeper feelings involved
in a person's behavior. (See ROLE REVERSAL; PSYCHODRAMA; AXIODRAMA).
(IP) 2. An activity during which a person attempts to think, speak,
and act/react as another, quite different person might. Often thought
of as acting without lines. Seen in a lot of pen and paper games,
where a person is given (or creates) a character to play (known
as a Player-Character or PC), who has a set of motivations, skills,
abilities and considerations that may be markedly different from
their own, and the person “playing” the character attempts
to be as that character would be. This may involve just describing
what the character would do in any given situation, or it may involve
putting on an accent, or dressing in a similar way to the character
being portrayed. These sorts of games, called Role Playing Games,
require a Game Master or Storyteller; someone who takes on the role
of “the world” as it were, telling the player what is
happening in the world, and how the others in the world (called
Non-Player Characters – NPCs) react, according to a set of
“game rules” that are often commercially produced, and
can be quite complex. Together they participate in a form of group
story telling, each filling in a role like a freeform play. Like
most pastimes that involve “escapism,” some players
become addicted to their game, and a very small minority may even
lose track of what is fantasy and what is reality. Most, however,
just enjoy the game for what it is. (RD)
ROLE REVERSAL: Is
where the major participants in an interaction change roles aimed
at transcending the habitual limitations of egocentricity and reach
a space where empathy for the other person's viewpoint or feeling
can be accurately assessed. (See ROLE PLAYING; PSYCHODRAMA; AXIODRAMA)
(IP)
ROMA: Known
by many names, the Roma are commonly known in English as Gypsies.
Various Roma populations may be found in Europe, the Middle East,
and North America. The Roma were traditionally travellers, and have
suffered much discrimination, especially in Europe. They were targeted,
along with the Jews, as primary victims in the Holocaust. The origin
of the Roma is not totally clear, although their language appears
to be of northern Indian origin. Their language was traditionally
unwritten, and not standardized and this accelerated the development
of local dialects into quite distinct forms. The result is that
many forms of the language of the Roma, known as Romany, are not
mutually intelligible. (AG)
ROS: See
RECREATION OPPORTUNITY SPECTRUM.
ROUNDUP: Glyphosphate,
a very widely used, systemic, non-selective herbicide. Monsanto
has genetically engineered some crops, notably soybeans, with glyphosphate
tolerance to facilitate weeding of fields. (RW)
RSI:
See REPETITIVE STRAIN INJURY.
RU-486:
The steriodal antiprogestin milepristone produced by Roussel
Uclaf as its trade name (now made by Danco Laboratories under the
tradename Mifeprex), which is capable of inducing early abortion
by inhibiting the secretion of progesterone. (DM+RD)
RUSSELL, BERTRAND: (1872-1970)
An English mathematician, philosopher and peace activist, Lord Russell
was one of the most prolific and influential philosophers of the
nineteenth and twentieth centuries. Principia Mathematica,
which he co-authored with Alfred North Whitehead, was an attempt
to translate mathematics into the language of formal logic, and
to formulate axioms from which all mathematics could be deduced.
This enterprise was frustrated by Kurt Godel's 1931 proof that all
such systems must be incomplete. But the book nonetheless laid the
foundations for the logical analysis of mathematics, language and
science. Even though this book was co-authored, it was essentially
a development and formal working-out of the ideas of an earlier
work, Principles of Mathematics , which Russell wrote himself.
Russell's contributions to almost every branch of philosophy were
immense. In an early paper, "On the notion of cause" he worked out
in detail Hume's substitution of the idea of regularity, for that of necessary causal connexion .
The outcome is that cause itself becomes an outmoded concept,
with is replaced by that of laws describing regularities of correlation
between one kind of event and another. This is the philosophical
background behind accepted thinking in medicine and epidemiology
today, in which it is rarely said that a certain kind of event causes
certain clinical symptoms. It is said instead that these events
are correlated or associated with those symptoms.
Russell's A
History of Western Philosophy (1945), has always been unpopular
among academic philosophers because of its readable and somewhat
flippant style, and a few inaccuracies. But it remains a valuable
reference book until this day. It has been consulted frequently
for the dates of most of the philosophers referred to in this Dictionary.
Russell's ethics was not only philosophical. He was willing to make
personal sacrifices for his principles. As an outspoken pacifist,
active in the No-Conscription
Fellowship during World War I, he was jailed for his activities.
He wrote his Introduction to Mathematical Philosophy while
serving his jail term.
Russell's intellectual courage is a model for
philosophers and bioethicists. Some people hang on to their ideas,
and hesitate to learn new things for fear that their long-held opinions
might be challenged. Russell was the opposite. He began every enquiry
with an open mind, ready to discover new truths. If what he discovered
happened to contradict what he had written before, he did not resist,
but accepted this as a further step towards truth. Although Russell
was a pacifist during World War I, he later recognised Nazism as
a threat to humanity, and supported the Allied war effort in World
War II. (FL)
RYLE.G: (1900-1976)
Gilbert Ryle was one of the most influential in the Oxford School
of Ordinary Language Philosophy. These philosophers taught that
the purpose of philosophy is to analyse our concepts. This is done
by observing and recording how we use words in ordinary language.
In his book The Concept of Mind , he argued that we do not
learn about the mind through neurobiology, but rather by analysing
how we use words, like thought, pain , and pleasure ,
which refer to our mental lives. (FL)
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